Skip to main content

Table 4 Computed Drug-likeness characteristics of the screened compounds

From: Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against dihydropteroate synthase

S/N

Bioactive compounds

Lipinski

Ghose

Veber

Egan

Muegge

Bioavailability Score

1

N,N-Diethylurea

0

No, 2

Yes

Yes

Yes

0.55

2

1,3- Cyclohexanediol

0

No, 2

Yes

Yes

No,1

0.55

3

6-Methyl-2-heptyne

0

No,2

Yes

Yes

No,2

0.55

4

N- Acetylethylenediamine

0

No,4

Yes

Yes

No, 2

0.55

5

Cyclopropanecarboxamide

0

No,3

Yes

Yes

No,2

0.55

6

N-Acetyl-L-methionine

0

Yes

Yes

Yes

No,1

0.56

7

Succinic acid

0

No,3

Yes

Yes

No,2

0.85

8

Thrimethoprim

0

Yes

Yes

Yes

Yes

0.56