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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: A novel therapeutic effect of mannitol-rich extract from the brown seaweed Sargassum ilicifolium using in vitro and in vivo models

Fig. 4

A) Microscopic inspection (40 × magnification) of RAW 264.7 (macrophages) cells, B) Human Dermal Fibroblasts (HDF) cell migration, C) Human Immortalized Keratinocyte (HaCaT) cell migration treated with S. ilicifolium (4 μg/μL) and negative control were evaluated over the course of 24 and 48 h. Cell migration observed after injury to the cellular monolayer from the in vitro scratch wound healing assay. Microscopic inspection (10× magnifications) of immediately after scratching (0 h) and after 24 and 48 h of wound healing. WT- control/without treatment, PC-positive control/Lipopolysaccharide (100 μg/mL), T- Treatment S. ilicifolium (4 μg/μL) aqueous extracts treated cells. Scale bar is 100 μm. Values are expressed as mean ± SE; Data is compared against values in the control group

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