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Table 7 Plasma biomarkers of liver and kidney function after 2000 mg/kg aqueous T. arjuna extract treatment

From: Antimalarial efficacy and toxicological assessment of medicinal plant ingredients of Prabchompoothaweep remedy as a candidate for antimalarial drug development

Group

Liver function test

AST (U/L)

ALT (U/L)

ALP (U/L)

Untreated control

85.42 ± 7.04

42.65 ± 4.88

85.28 ± 4.13

7% tween 80

87.20 ± 0.80 c

41.75 ± 3.70

85.03 ± 3.16

T. arjuna extract

90.33 ± 1.45 b

41.24 ± 0.95

88.95 ± 4.72

 

Kidney function test

 

BUN (mg/dL)

Cr (mg/dL)

Untreated control

26.42 ± 4.32

0.66 ± 0.05

7% tween 80

27.55 ± 0.45

0.66 ± 0.04

T. arjuna extract

25.95 ± 2.91

0.64 ± 0.02

  1. Data represent mean ± SEM (n = 5 per group)
  2. aCompared to untreated control; bcompared to 7% Tween 80; ccompared to 2000 mg/kg extract, p < 0.05