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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Fig. 1

Effects of TJ-41 on C2C12 myotubes. A Expression of atrogin-1 and MuRF1 after 24 h of serum deprivation (n = 3). Effects of TJ-41 extraction on expression of atrogin-1 and MuRF1. Concentrations of the extract are 1, 10 or 100 µg/mL (n = 3). Significant differences were detected by the post-hoc Tukey-Kramer test. B Phosphorylation of Akt, p70, mTOR, FoxO1, and AMPK in TJ-41-treated myotubes (western blot). These images were cropped from the original gels and blots. *p < 0.05, **p < 0.01, ***p < 0.001. NS indicates “not significant”

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