Table 5 Cytotoxicity studies of the methanolic leaf extracts of Catharanthus roseus against the MDA-MB-231 Cell lines
Samples | Concentration μg/ ml | OD @ 590 nm | % Inhibition | IC50 μg/ ml |
|---|---|---|---|---|
Control | 0 | 0.743 | 0.00 | – |
Vinblastine | 3.125 | 0.599 | 19.38 | 21.54 |
6.250 | 0.560 | 24.63 | ||
12.500 | 0.437 | 41.18 | ||
25.000 | 0.292 | 60.70 | ||
50.000 | 0.165 | 77.79 | ||
100.000 | 0.092 | 87.58 | ||
Methanolic extract of C. roseus | 10.00 | 0.614 | 17.36 | 57.64 |
20.00 | 0.534 | 28.13 | ||
40.00 | 0.442 | 40.51 | ||
80.00 | 0.344 | 53.70 | ||
160.00 | 0.246 | 66.89 | ||
320.00 | 0.169 | 77.25 |