Fig. 4

Measurement of bioenergetics profile of psoralidin, isobavachalcone, and bavachinin. OCR (A, B, and C) and ECAR (D) were measured in real time, and the concentrations of psoralidin, isobavachalcone, and bavachinin were at 446.43, 30.86, and 59.17 μM respectively. (E) Each mitochondrial parameter was calculated derived from the data in A, B and C. Abbreviations and the corresponding parameters are as follows: reserve capacity (RC), maximal respiratory capacity (MRC), basal respiration (BR), proton leak (PL), ATP-linked production (ALP), and non-mitochondrial respiration (NMR). Data represent mean ± SD, n = 3 (*P < 0.05, ***P < 0.001, ****P < 0.0001 versus control OCR)