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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

Fig. 7

The effect and mechanism of LE (Glycyrrhiza glabra) acting on TGF-β1-activated NPDFs. By inhibiting the MAPK/ERK-1/2 signaling pathway, LE prevents downstream α-SMA from differentiating fibroblasts into myofibroblasts and consequently impairs the production of ECM, including FBN and type I collagen

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