Fig. 7From: Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic studyThe effect and mechanism of LE (Glycyrrhiza glabra) acting on TGF-β1-activated NPDFs. By inhibiting the MAPK/ERK-1/2 signaling pathway, LE prevents downstream α-SMA from differentiating fibroblasts into myofibroblasts and consequently impairs the production of ECM, including FBN and type I collagenBack to article page