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Table 5 Interaction between placebo and yokukansan groups on change after 12 weeks of smoking cessation intervention

From: Randomized double-blind placebo-controlled multicenter trial for the effects of a polyherbal remedy, Yokukansan (YiganSan), in smokers with depressive tendencies

Placebo group (n = 53)

Yokukansan group (n = 55)

interaction

[baseline and 12-week]x [Placebo and Yokukansan]

 

Mean difference

95% Confident interval

d a

Mean difference

95% Confident interval

d a

P value b

pη2 c

BMI (kg/m2)

0.45

0.12,

0.17

0.382

0.52

0.29,

0.76

0.616

.705

0.002

SBP (mm Hg)

-0.12

-5.92,

5.68

0.006

5.87

1.07,

10.7

0.337

.112

0.026

DBP (mm Hg)

-1.41

-5.17,

2.35

0.106

1.70

-.165,

5.04

0.140

.217

0.012

CO (ppm)

-14.1

-17.2,

-11.0

1.369

-13.5

-16.9,

-10.0

1.131

.781

0.014

SDS test score

-3.51

-5.83,

-1.19

0.417

-4.56

-6.81,

-2.30

0.551

.518

0.000

POMS score

Tension-Anxiety(T-A)

-1.59

-2.48,

-0.71

0.518

-1.60

-2.85,

-0.35

0.363

.992

0.001

Depression-Dejection(D)

-0.12

-0.95,

0.71

0.042

-1.88

-3.11,

-0.65

0.436

.019

0.024

Anger-Hostility (A-H)

-0.08

-1.26,

1.10

0.020

-1.26

-2.59,

0.07

0.270

.186

0.001

Vitality(V)

1.16

-0.02,

2.34

0.283

1.14

-0.32,

2.60

0.222

.980

0.000

Fatigue(F)

-0.49

-1.79,

0.81

0.108

-2.14

-3.43,

-0.85

0.472

.073

0.006

Confusion(C)

-0.57

-1.40,

0.26

0.197

-1.00

-1.80,

-0.20

0.356

.457

0.002

  1. Data are presented as the mean ± standard deviation
  2. BMI Body mass index, SBP Systolic blood pressures, DBP Diastolic blood pressures, CO Carbon monoxide, SDS Test score, self-rating depression scale test score, POMS mood state profile
  3. a effect size difference (Cohen d)
  4. b two-way analysis of variance to determine the interaction between time (baseline and 12-week) and group (placebo group and Yokukansan group)
  5. c effect size for interaction (Partial eta squared)