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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Ascorbic acid 6-palmitate modulates microglia M1/M2 polarization in lipopolysaccharide-stimulated BV-2 cells via PERK/elF2α mediated endoplasmic reticulum stress

Fig. 5

Graphical summary of the results. On exposure to LPS, BV-2 cells were activated toward M1 polarization phenotype through GRP78/PERK/elF2α/CHOP mediated severe ER stress. L-AP as a potential PERK inhibitor possessed its effect on the reconstruction of microglia M1/M2 polarization balance in LPS-stimulated BV-2 cells via modulating PERK/elF2α mediated ER stress

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