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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway

Fig. 5

RT-qPCR showing cytosolic expression of (A) Nrf-2/Keap1/HO-1-mediated antioxidant pathway, (B) inflammatory (IL-β and TNF-α) and NF-κB (ELISA) pathway, and (C) apoptotic (Bcl-2 and Bax) pathway in the kidney homogenate from diabetic kidney treated with C. anthelminticum fixed oil and its fractions. The values are expressed as the mean ± S.E.M. Statistical analysis was carried out using the One-way ANOVA followed by LSD multiple comparisons post hoc test, *p < 0.05 versus Normal Control (NC); #p < 0.05 versus DM Control. Abbreviations: DM-C: DM + 1 mL/kg distilled water, DM-Glic: DM + 200 mg/kg Glicalized, FO: DM + 200 mg/kg C. anthelminticum fixed oil, HF: DM + 200 mg/kg hexane fraction, CF: DM + 200 mg/kg chloroform fraction and EF: DM + 200 mg/kg ethanol fraction

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