Fig. 8

Effect of the G.s Maxim ‘s ethyl acetate extraction on the HIF/NF-KB signaling pathways and hypoxia-induced apoptosis. A. The protein levels of HIF-1α, p65, Bcl-2 and Bax were measured by western blotting; B. Relative protein level of HIF-1α; C. Relative protein level of p65; D. The ratio of the relative protein levels of Bcl-2 to Bax. β-tubulin served as a loading control. Bars represent the mean ± S.D. from three independent experiments; compare with control group, #p < 0.05, ##p < 0.01; compare with model group, *p < 0.05, **p < 0.01