Table 2 Characteristics of curcuminoids formulations applied in the included studies
Studies | Formulations | Source | Compounds or species, concentration | Purity or encapsulation rate (%) | Quality control reported? (Y/N) | Chemical analysis reported? (Y/N) |
|---|---|---|---|---|---|---|
Kuptniratsaikul V 2009 [56] | CL extract | Thai Government Pharmaceutical Organization | Curcuminoids extracted from the dried rhizomes of CL, 250 mg per capsule | Not mention | Y – Prepared according to the Good Manufacturing Procedures Standard | N |
Kuptniratsaikul V 2014 [57] | CL extract | Thai Government Pharmaceutical Organization | Curcuminoids extracted from the dried rhizomes of CL, 250 mg per capsule | 75% – 85% | Y – Prepared according to the Good Manufacturing Procedures Standard | Y – HPLC |
Nakagawa Y 2014 [61] | Theracurmin® | Theravalues, Tokyo, Japan | Surface-controlled water-dispersible nano-curcumin, 30 mg per capsule | Not mentioned | N | N |
Panahi Y 2014 et al. [62] | C3 complex® | Sami Labs Ltd., Bangalore, India | Curcuminoids and bioperine, 500 mg and 5 mg per capsule | Not mentioned | N | N |
Srivastava S 2016 [65] | Haridra® | Himalaya Drug Company Bangalore, India | Curcuminoids extracted from rhizomes of CL, 500 mg per capsule |  ≥ 95% | N | Y – HPTLC |
Haroyan A 2018 [66] | CuraMed® | EuroPharma, USA | Curcuminoids and volatile oil extracted from rhizomes of CL, 500 mg and 49–52 mg per capsule | Not mentioned | Y – Prepared according to the Good Manufacturing Practice | N |
Panda SK 2018 [67] | Curene® | Olene Life Sciences Pvt. Ltd., Chennai, India | Curcuminoids and volatile oil extracted from rhizomes of CL, 500 mg per capsule |  ≥ 95% | Y– Developed using proprietary technology called Aqueosome® | N |
Gupte PA 2019 [58] | Longvida® | Verdure Sciences, USA | Solid lipid curcumin particles containing 400 mg patented lipophilic matrix and 80 mg curcumin per capsule | Not mentioned | Y – Made with SLCP™ Technology | N |
Herotin Y 2019 [68] | FLEXOFYTOL® | Tilman SA, Baillonville, Belgium | Curcuminoids extracted from extracted from rhizomes of CL, polysorbate 80 [E433]as an emulsifier, and citric acid [E330] as an acidity regulator, 46.67 mg per capsule | Pharmaceutical-grade | N | N |
Shep D 2019 [59] | BCM-95® | Arjuna Natural Ltd., Kerala, India | Curcuminoids and volatile oil extracted from rhizomes of CL, 500 mg per capsule |  ≥ 95% | N | N |
Wang Z 2020 [69] | Turmacin Plus | Natural Remedies Pvt., Bengaluru | Curcuminoids and turmerosaccharides extracted from rhizomes of CL, 500Â mg per capsule | 20% | N | N |
Atabaki M 2020 [70] | SinaCurcumin® | Exir Nano Sina Company, Tehran, Iran | Nanomicelle consists of curcumin, 80 mg per capsule | ≈ 100% | N | N |
Hashemzadeh K 2020 [71] | SinaCurcumin® | Exir Nano Sina Company, Tehran, Iran | Nanomicelle consists of curcumin, 80 mg per capsule | ≈ 100% | N | N |
Singhal S 2021 [60] | BCM-95® | Arjuna Natural Pvt. Ltd., India | Curcuminoids and volatile oil extracted from rhizomes of CL, 500 mg per capsule |  ≥ 95% | N | Y – UPLC, FT-NIR spectrometer |
Lopresti L 2022 [72] | Curcuge® | Dolcas Biotech LLC | Standardised curcuminoids extract, 500 mg per capsule | ≈ 50% | N | N |