Skip to main content
Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Reproductive and endocrine effects of artemisinin, piperaquine, and artemisinin-piperaquine combination in rats

Fig. 2

The representative histological photomicrographs of the adrenal gland (top row) and ovary (bottom row) of female rats after administered with ATQ for 14 days. (A) Control adrenal gland (×100); (B) Adrenal gland of 80 mg/kg ATQ (×40). Vasodilation and hyperemia in adrenal cortex and medulla; (C) Adrenal gland of 80 mg/kg ATQ (×400). Vacuolar degeneration and hyperemia; (D) Adrenal gland of 80 mg/kg ATQ (×40). Brown fat attached to the adrenal gland; (E) Control ovary (×40); (F) Ovary of 80 mg/kg ATQ (×40). Hyperemia in the luteal surface; (G) Ovary of 80 mg/kg ATQ (×40). Numerous but small corpus luteum, and disordered follicle development (mainly primary and secondary follicles, few or no mature follicles). Yellow, blue, and black circles are representative of the corpus luteum, primary follicle, and secondary follicle, respectively. Arrows indicate histopathological changes

Back to article page