Month | Dose (mg/kg) | WBC(K/μL) | LYM(K/μL) | MON(K/μL) | NEU(K/μL) | EO(K/μL) | BA(K/μL) | RBC(M/μL) | MCV(fL) | HCT(%) | MCH(pg) | MCHC(g/dL) | Hb(g/dL) | RDW-SD(fL) | PLT(K/μL) | MPV(fL) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
4 | Control | 5.27 ± 1.07 | 3.33 ± 0.57 | 0.54 ± 0.23 | 0.93 ± 0.47 | 0.13 ± 0.05 | 0.20 ± 0.05 | 8.03 ± 0.44 | 49.57 ± 1.22 | 39.80 ± 1.84 | 18.44 ± 0.52 | 37.20 ± 1.05 | 14.78 ± 0.59 | 33.56 ± 0.50 | 649 ± 163 | 6.15 ± 0.54 |
300 | 5.50 ± 1.31 | 3.57 ± 0.73 | 0.57 ± 0.29 | 0.89 ± 0.41 | 0.11 ± 0.06 | 0.19 ± 0.06 | 7.91 ± 0.37 | 49.27 ± 2.07 | 38.91 ± 1.13 | 18.36 ± 0.78 | 37.25 ± 0.51 | 14.50 ± 0.40 | 33.49 ± 0.71 | 743 ± 58 | 6.09 ± 0.47 | |
8 | Control | 4.09 ± 1.04 | 2.03 ± 0.34 | 0.30 ± 0.11 | 1.15 ± 0.73 | 0.00 ± 0.00 | 0.20 ± 0.11 | 8.27 ± 0.25 | 51.65 ± 1.66 | 42.70 ± 1.95 | 17.63 ± 0.59 | 34.13 ± 0.64 | 14.58 ± 0.46 | 34.60 ± 0.39 | 780 ± 47 | 6.17 ± 0.14 |
300 | 3.67 ± 0.72 | 1.73 ± 0.33 | 0.27 ± 0.08 | 1.05 ± 0.42 | 0.07 ± 0.05 | 0.20 ± 0.06 | 8.22 ± 0.23 | 51.18 ± 1.50 | 42.02 ± 0.91 | 17.63 ± 0.56 | 34.43 ± 0.56 | 14.48 ± 0.28 | 34.43 ± 0.29 | 804 ± 140 | 6.13 ± 0.22 | |
12 | Control | 6.52 ± 1.66 | 1.82 ± 0.89 | 3.27 ± 0.76 | 0.47 ± 0.14 | 0.07 ± 0.08 | 0.30 ± 0.06 | 8.16 ± 0.41 | 13.78 ± 0.78 | 44.98 ± 3.50 | 55.10 ± 2.40 | 16.93 ± 0.40 | 30.75 ± 0.98 | 17.60 ± 0.52 | 860 ± 83 | 6.20 ± 0.31 |
300 | 4.12 ± 1.02* | 1.23 ± 0.38 | 2.10 ± 0.51 | 0.37 ± 0.12 | 0.00 ± 0.00 | 0.18 ± 0.04 | 8.26 ± 0.21 | 13.98 ± 0.66 | 45.23 ± 2.18 | 54.77 ± 2.18 | 16.95 ± 0.65 | 30.97 ± 0.28 | 17.85 ± 0.29 | 759 ± 150 | 6.47 ± 0.34 | |
Female | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
4 | Control | 4.23 ± 1.00 | 3.09 ± 0.78 | 0.24 ± 0.11 | 0.37 ± 0.17 | 0.19 ± 0.11 | 0.13 ± 0.05 | 6.78 ± 1.21 | 55.54 ± 6.29 | 36.98 ± 3.93 | 22.08 ± 5.26 | 39.32 ± 4.46 | 14.40 ± 0.59 | 34.45 ± 2.49 | 575 ± 88 | 5.93 ± 0.25 |
300 | 5.08 ± 1.49 | 3.70 ± 1.14 | 0.32 ± 0.10 | 0.52 ± 0.20 | 0.22 ± 0.20 | 0.15 ± 0.07 | 7.16 ± 0.53 | 54.16 ± 2.09 | 38.74 ± 2.52 | 20.37 ± 1.81 | 37.57 ± 2.23 | 14.50 ± 0.60 | 33.66 ± 0.95 | 619 ± 111 | 5.79 ± 0.32 | |
8 | Control | 3.52 ± 1.59 | 2.17 ± 0.99 | 0.18 ± 0.10 | 0.68 ± 0.46 | 0.13 ± 0.15 | 0.17 ± 0.08 | 8.02 ± 0.33 | 59.77 ± 1.26 | 47.90 ± 2.22 | 16.75 ± 0.63 | 27.98 ± 0.65 | 13.40 ± 0.53 | 35.32 ± 0.88 | 838 ± 158 | 5.93 ± 0.35 |
300 | 2.81 ± 1.03 | 1.72 ± 0.50 | 0.15 ± 0.05 | 0.57 ± 0.41 | 0.10 ± 0.11 | 0.13 ± 0.05 | 8.09 ± 0.51 | 55.82 ± 3.66* | 45.10 ± 2.51 | 16.53 ± 0.88 | 29.70 ± 1.76* | 13.37 ± 0.67 | 35.47 ± 1.17 | 818 ± 146 | 6.15 ± 0.24 | |
12 | Control | 2.64 ± 0.64 | 0.74 ± 0.36 | 1.38 ± 0.32 | 0.21 ± 0.08 | 0.00 ± 0.00 | 0.11 ± 0.04 | 7.54 ± 0.48 | 13.08 ± 0.61 | 42.60 ± 1.94 | 56.56 ± 2.62 | 17.38 ± 0.81 | 30.71 ± 0.64 | 16.98 ± 0.78 | 712 ± 168 | 6.16 ± 0.39 |
300 | 2.49 ± 0.42 | 0.68 ± 0.16 | 1.36 ± 0.23 | 0.19 ± 0.04 | 0.00 ± 0.00 | 0.10 ± 0.00 | 7.31 ± 1.32 | 12.61 ± 1.95 | 41.34 ± 6.01 | 57.10 ± 3.95 | 17.36 ± 0.95 | 30.45 ± 0.59 | 17.18 ± 0.33 | 760 ± 77 | 6.08 ± 0.35 |