Skip to main content

Table 2 Growth inhibition and cytotoxicity of paclitaxel on selected human carcinoma cell lines

From: Anti-inflammatory, cytotoxicity and antilipidemic properties: novel bioactivities of true cinnamon (Cinnamomum zeylanicum Blume) leaf

Carcinoma cell line

% Net growth

GI 50

LC 50

TGI

Concentration (μg/mL)

0.62

1.25

2.5

5

10

MCF 7

62.91 ± 5.15

35.20 ± 3.09

7.28 ± 1.13

−95.49 ± 1.82

−97.98 ± 0.87

1.01 ± 0.04

3.82 ± 0.03

2.41 ± 0.02

HePG2

69.54 ± 1.94

50.06 ± 0.95

23.44 ± 6.21

−92.97 ± 2.39

−92.97 ± 1.27

1.34 ± 0.04

4.03 ± 0.08

2.68 ± 0.06

AN3CA

7.22 ± 1.49

−4.10 ± 3.94

−33.98 ± 1.51

−37.05 ± 0.98

–

0.16 ± 0.01

4.91 ± 0.55

0.96 ± 0.08

  1. Results expressed as mean ± SE. (n = 3 each); MCF 7, HePG2 and AN3CA: r2 = 0.99, 0.98 and 0.92 respectively; − 10 μg/mL concentration didn’t study for the AN3CA cell line
  2. GI50 concentration of extract at 50% inhibition of cancer cells growth compared to control, LC50 concentration of extract which kills 50% of cancer cells, TGI Total Growth Inhibition: the concentration of extract which halt the cancer cells growth completely