Table 3 Changes in pharmacodynamics (PD) parameters of control and after administration of GWE, EWE, SWE, and acarbose with sucrose or starch ingestions

From: Selected coffee (Coffea arabica L.) extracts inhibit intestinal α-glucosidases activities in-vitro and postprandial hyperglycemia in SD Rats

Groups	PD Parameters
Groups	Cmax (mg/dL)	Tmax (hr)	AUCt (hr·mg/dL)
Sucrose 2.0 g/kg	222.3 ± 16.0	0.7 ± 0.3	516.0 ± 29.0
Acarbose 5.0 mg/kg	137.4 ± 8.3^***	0.8 ± 0.3	376.2 ± 17.2^***
GWE 0.5 g/kg	208.8 ± 14.4	0.8 ± 0.3	496.3 ± 23.9
EWE 0.5 g/kg	182.5 ± 15.4^**	1.4 ± 0.9	434.8 ± 50.8^*
SWE 0.5 g/lg	191.0 ± 9.1^**	1.0 ± 0.0^*	482.3 ± 12.7
Starch 2.0 g/kg	236.2 ± 25.1	0.5 ± 0.0	529.1 ± 13.4
Acarbose 5.0 mg/kg	144.1 ± 18.8^***	1.3 ± 0.5^**	389.0 ± 36.8^***
GWE 0.5 g/kg	218.3 ± 20.6	1.0 ± 0.6	536.3 ± 49.4
EWE 0.5 g/kg	191.3 ± 13.2^**	0.8 ± 0.3^*	490.5 ± 34.6
SWE 0.5 g/lg	222.9 ± 30.1	0.5 ± 0.0	548.9 ± 47.2

The results were expressed as mean ± S.D. All parameters were compared between control and treatment group (GWE, EWE, SWE, and Acarbose) by unpaired Student’s t-test (*p < 0.05; **p < 0.01; and ***p < 0.001)

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