Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype

Table 3 Mean fold change in the expression of genes involved in IMD-pathway upon formulation feeding

Genes	Mean -∆∆CT (+SD; N = 3 biological replicates in each) of expression of genes of IMD-pathway in *GMR-GAL4 > UAS-127Q/CyO-GFP* with respect to larvae fed on regular food (> 2 ∆∆CT value is considered significant i.e., p < 0.05 and is marked with *)
Genes	Guduchi	Madhuyashti
Tab2	0.96 + 0.06	1.2 + 0.26
Imd	3.48 + 0.17*	3.87 + 0.4*
Fadd	1.67 + 0.04	1.35 + 0.07
Dredd	0.89 + 0.33	0.98 + 0.52
Tak1	4.67 + 0.33*	4.38 + 0.23*
Relish	1.36 + 0.56	1.23 + 0.32

ISSN: 2662-7671