Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype

Table 2 Mean fold change in the expression of genes involved in Toll-pathway upon formulation feeding

Genes	Mean -∆∆CT (+SD; N = 3 biological replicates in each) of expression of various upstream genes of Toll-pathway in *GMR-GAL4 > UAS-127Q/CyO-GFP* with respect to larvae fed on regular food (> 2 ∆∆CT value is considered significant i.e., p < 0.05 and is marked with *)
Genes	Guduchi	Madhuyashti
Dorsal	1.43 + 0.07	1.33 + 0.1
Spatzle	2.45 + 0.4*	3.68 + 0.4*
Myd88	0.84 + 0.03	0.73 + 0.13
Cactus	0.34 + 0.11	0.54 + 0.09
Tube	0.59 + 0.34	0.63 + 0.16
Pelle	0.83 + 0.45	0.67 + 0.22

ISSN: 2662-7671