Fig.8

Protective effects of SAA on the organ injury and function in LPS-induced DIC rats. At 3 h after LPS administration, an automatic analyzer was used to detect the ALT (A) and Cre (B) levels in plasma. Data were presented as the mean ± SD. n = 8 in the control group, n = 11 in the LPS group, and n = 9 in the LPS + SAA (40 mg/kg) group. **P < 0.01, ***P < 0.001 compared with the Control group. ^#P < 0.05, ^###P < 0.001 compared with the LPS group. ALT, alanine aminotransferase. Cre, creatinine. At 3 h after LPS administration, lung histopathology of rats (H&E staining): lung H&E staining (C) and lung injury score (D). The original magnifications are 100× and 400×. The red, green, blue, yellow, and orange arrows indicate alveolar epithelial cells, lymphocytes, neutrophils, alveolar macrophages, and fibroblasts, respectively. Results are presented as mean ± SD (n = 6 in each group). ***P < 0.001 compared with the Control group. ^###P < 0.001 compared with the LPS group. Statistical tests used were t-tests