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Table 8 Effect of GlucoMedix® on glucose concentrations in alloxan-induced hyperglycemic rats

From: Correction: GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

 

Glucose (mg/dl)

Group/dose (mg/kg)

BASAL

0days

7days

14days

21days

28days

Control (uninduced)

90.3 ± 1.49

92.0 ± 1.63 &&

93.3 ± 2.36 &&

94.3 ± 2.43 &&

96.2 ± 2.41 &&

98.5 ± 2.36 &&

Negative Control (induced)

92.7 ± 4.50

495.7 ± 20.62 **

528.2 ± 20.42 **

545.7 ± 15.91**

566.3 ± 12.34 **

579.0 ± 11.87 **

Glibenclamide 10

90.3 ± 2.34

500.0 ± 17.03 **

287.8 ± 18.76 *&

137.5 ± 8.78 *&&

107.3 ± 4.55 &&

92.7 ± 1.97 &&

GlucoMedix 250

90.2 ± 3.89

509.7 ± 13.83 **

482.5 ± 10.90 **&&

448.7 ± 12.49 **&

418.8 ± 16.10 **&

396.5 ± 13.38 **&

GlucoMedix 500

94.3 ± 3.77

512.5 ± 14.63 **

324.2 ± 17.06 **&

268.2 ± 15.83 *&

207.2 ± 2.54 *&&

177.0 ± 6.71*&&

GlucoMedix 1000

93.3 ± 3.33

501.5 ± 9.54 **

305.0 ± 8.00 **&

216.3 ± 4.93 *&&

146.2 ± 13.47 *&&

102.2 ± 4.02 &&

  1. Values are expressed as mean ± SD. n= 5. Statistical significance was * p<0.05, ** p<0.001 compared to control group (uninduced); & p<0.05, && p<0.001 compared to negative control group (induced)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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