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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Alpinia officinarum Rhizome ameliorates the UVB induced photoaging through attenuating the phosphorylation of AKT and ERK

Fig. 7

UVB-induced reduction of COL1A1 and increase of MMP-1a were restored by administration of WEAOR as well as by signaling inhibitors (PD98059: MEK inhibitor and LY294002: AKT inhibitor). The effects of WEAOR, PD98059, LY294002 on the UVB-induced activation of ERK and AKT was estimated by western blotting (A, B). The UVB-mediated expression of COL1A1 and MMP-1a on NIH-3T3 cells was estimated by qRT-PCR (C, D). Experiments were conducted in triplicate and repeated three times with similar results. Each data value shown is mean ± SD. Different letters show significant differences between groups (P < 0.05)

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