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Table 4 Effects of bioprocessed Ecklonia cava and its purified products on Th1, Th2, and Treg cytokine release into serum and BALF from OVA-sensitized/challenged mice

From: Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

 

Cytokine Production (ng/mL)

in BALF

in Serum

IL-4

IL-5

IL-13

IL-2

IL-12

IL-10

Vehicle

8.3 ± 0.7e

11.7 ± 1.3e

11.4 ± 1.4e

18.3 ± 1.7a

222 ± 23a

88.4 ± 7.9a

OVA only

82.7 ± 5.8a

133 ± 13a

131 ± 15a

7.9 ± 0.8e

132 ± 12e

34.8 ± 4.2f

EC-1

75.9 ± 6.2ab

115.9 ± 9.3ab

107.8 ± 9.7b

9.2 ± 1.4d

165 ± 15d

42.7 ± 3.7e

EC-2

72.7 ± 5.4b

108 ± 11b

113 ± 14ab

8.9 ± 0.9d

159 ± 14d

40.7 ± 3.7e

EC-F-1

53.6 ± 4.9d

83.6 ± 7.2d

71.2 ± 8.3d

13.2 ± 1.7b

190 ± 16b

66.9 ± 5.8b

EC-F-2

59.2 ± 5.2cd

88.9 ± 6.9cd

78.6 ± 5.6cd

12.6 ± 0.8b

176 ± 15bc

58.2 ± 5.2c

EC-F-3

63.9 ± 5.9c

85.3 ± 7.3d

86.3 ± 4.9c

10.7 ± 1.3c

172 ± 19c

49.6 ± 5.5d

EC-F-4

66.2 ± 7.2bc

91.2 ± 7.4c

81.2 ± 9.6c

11.5 ± 1.7bc

181 ± 17b

52.2 ± 6.2d

  1. Data are shown as the mean ± SD of three independent repetitions. PBS was used as vehicle. Values in each column with the same superscript letters a-e are not significantly different between groups at p < 0.05