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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

Fig. 4

Decreased levels of thymic stromal lymphopoietin (TSLP) level in bronchoalveolar lavage fluid (BALF) from OVA-sensitized/challenged allergic model mice orally administered with bioprocessed Ecklonia cava and its purified products. BALF was collected from Ecklonia cava extracts-administered sensitized/challenged Balb/c mice by lavaging tracheas with PBS. After centrifugation, supernatant was recovered from each mouse group or quantitation of TSLP level in BALF using the ELISA kit. Representation: vehicle (−), negative control not sensitized/challenged with OVA; vehicle (+), OVA-sensitized/challenged positive control; EC-1, Ecklonia cava water extracts (40 mg/kg body weight); EC-2, Ecklonia cava 70% ethanol extracts (20 mg/kg body weight); EC-F-1, bioprocessed Ecklonia cava extract (40 mg/kg body weight); EC-F-2, Solid-liquid separation fraction of bioprocessed Ecklonia cava (12 mg/kg body weight); EC-F-3, Water-soluble fraction of bioprocessed Ecklonia cava (11 mg/kg body weight); EC-F-4, Polysaccharide fraction of bioprocessed Ecklonia cava (3 mg/kg body weight), mouse groups dietary administered with all extracts respectively. Data are expressed as mean ± SD (n = 10). Bars sharing a common letter are not significantly different between groups at p < 0.05

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