Fig. 4From: Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthmaDecreased levels of thymic stromal lymphopoietin (TSLP) level in bronchoalveolar lavage fluid (BALF) from OVA-sensitized/challenged allergic model mice orally administered with bioprocessed Ecklonia cava and its purified products. BALF was collected from Ecklonia cava extracts-administered sensitized/challenged Balb/c mice by lavaging tracheas with PBS. After centrifugation, supernatant was recovered from each mouse group or quantitation of TSLP level in BALF using the ELISA kit. Representation: vehicle (−), negative control not sensitized/challenged with OVA; vehicle (+), OVA-sensitized/challenged positive control; EC-1, Ecklonia cava water extracts (40 mg/kg body weight); EC-2, Ecklonia cava 70% ethanol extracts (20 mg/kg body weight); EC-F-1, bioprocessed Ecklonia cava extract (40 mg/kg body weight); EC-F-2, Solid-liquid separation fraction of bioprocessed Ecklonia cava (12 mg/kg body weight); EC-F-3, Water-soluble fraction of bioprocessed Ecklonia cava (11 mg/kg body weight); EC-F-4, Polysaccharide fraction of bioprocessed Ecklonia cava (3 mg/kg body weight), mouse groups dietary administered with all extracts respectively. Data are expressed as mean ± SD (n = 10). Bars sharing a common letter are not significantly different between groups at p < 0.05Back to article page