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Table 2 Effect of ethanolic leaf extract of cannabis on sperm parameters in Wistar rats

From: Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Group

Normal control

Vitamin C

5 mg/kg BW

10 mg/kg BW

20 mg/kg BW

Sperm volume (mL)

1.59 ± 0.08a

1.71 ± 0.01a

1.58 ± 0.10a

1.72 ± 0.02a

1.69 ± 0.04a

Concentration count (× 106 mL)

133.33 ± 6.67a

293.33 ± 6.67b

263.33 ± 13.33ab

183.33 ± 16.67c

216.67 ± 12.02d

Motile count (106 mL)

56.67 ± 3.33a

246.67 ± 3.33b

276.67 ± 3.33ab

176.67 ± 3.33c

173.67 ± 6.67c

Total count (× 106 mL})

193.33 ± 9.28a

504.33 ± 8.67b

442.00 ± 8.00c

317.00 ± 27.00ab

307.33 ± 30.67ab

Motility (%)

50.00 ± 0.00a

85.00 ± 1.00b

78.67 ± 12.86a

75.67 ± 14.33b

71.67 ± 14.33b

Fast

51.67 ± 3.33a

83.33 ± 0.88a

72.33 ± 9.59a

64.67 ± 12.99a

69.67 ± 13.45a

Slow

50.00 ± 4.53c

17.67 ± 2.88a

41.0000 ± 1.45b

51.0000 ± 1.00c

54.00 ± 2.08c

N

51.00 ± 2.08a

82.00 ± 2.00c

69.33 ± 11.39a

70.67 ± 12.99a

70.33 ± 13.86a

TD

22.67 ± 1.45c

8.00 ± 0.57a

11.67 ± 5.54a

13.33 ± 5.33a

13.00 ± 6.50a

ND

11.00 ± 0.57c

4.33 ± 0.33a

7.00 ± 3.05a

7.00 ± 3.00a

7.33 ± 3.84a

HD

13.00 ± 2.08b

5.00 ± 1.73a

6.67 ± 2.33a

6.00 ± 5.00a

7.33 ± 4.33a

  1. The values are expressed as means of 3 replicates ± SEM
  2. abcdp < 0.05 vs normal control
  3. N Normal, TD Defected tail, ND Defected neck, HD Defected head