Table 9 Effects of E. globulus leaf fractions on body weight and temperature against P. berghei infected mice in the prophylactic test

2%tween80(10 ml/kg)

24.83 ± 0.60

22.42 ± 0.55

−9.72 ± 0.76

35.33 ± 0.33

32.67 ± 0.46

−7.55 ± 0.88

CQ(25 mg/kg)

25.67 ± 0.76

26.47 ± 0.56

3.28 ± 1.43^a3

35.85 ± 0.36

35.95 ± 0.31

0.30 ± 0.83

CF (mg/kg) 100

26.17 ± 1.19

25.18 ± 1.06

−3.66 ± 0.81^a1b2

36.63 ± 0.33

35.33 ± 0.44

−3.55 ± 0.88

 200

24.33 ± 0.95

23.75 ± 0.81

−2.26 ± 1.28^a2b1

35.60 ± 0.46

35.32 ± 0.47

−0.74 ± 1.55^a3

 400

24.33 ± 1.17

24.53 ± 1.32

0.72 ± 1.40^a3

36.40 ± 0.51

36.33 ± 0.33

−0.12 ± 1.29^a3

EAF (mg/kg) 100

26.17 ± 0.91

5.00 ± 0.85

−4.44 ± 0.31^b2

35.58 ± 0.37

34.70 ± 0.40

−2.46 ± 1.09^a1

 200

25.93 ± 1.26

25.22 ± 0.95

−2.53 ± 1.11^a2b1

35.92 ± 0.49

35.52 ± 0.43

−1.10 ± 0.54^a3

 400

23.17 ± 1.08

24.02 ± 1.02

3.82 ± 1.49^a3

36.83 ± 0.38

36.92 ± 0.08

0.28 ± 0.97^a3

DW (10 ml/kg)

27.67 ± 0.71

25.13 ± 0.64

−9.15 ± 0.50

36.27 ± 0.35

33.62 ± 0.44

−7.32 ± 0.64

CQ (25 mg/kg)

25.67 ± 0.76

26.47 ± 0.56

3.28 ± 1.43^a3

35.85 ± 0.36

35.95 ± 0.31

0.30 ± 0.83^a3

AF (mg/kg) 100

25.67 ± 0.88

24.33 ± 0.99

−5.28 ± 1.13^b3

35.88 ± 0.47

34.43 ± 0.45

−4.03 ± 0.65

 200

28.42 ± 1.07

27.70 ± 0.83

−2.36 ± 1.19^a2b1

35.57 ± 0.39

35.05 ± 0.28

−1.44 ± 0.40^a2

 400

25.93 ± 0.65

26.00 ± 0.43

0.40 ± 1.47^a3

36.38 ± 0.28

36.25 ± 0.28

−0.36 ± 0.66^a3