Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice

Table 8 Chemo-prophylactic activity of E. globulus leaf solvent fractions against P. berghei infected mice

Treatments	% parasitemia (D7)	%parasitemia suppression	Mean survival time (day)
2% tween 80 (10 ml/kg)	36.67 ± 1.28	0.00 ± 0.00	9.67 ± 0.80
CQ (25 mg/kg)	5.50 ± 0.56	85.10 ± 1.19	28.33 ± 0.49^a3
CF (mg/kg) 100	19.17 ± 1.22	48.19 ± 4.43^a3b3	14.33 ± 0.80^a2b3
200	14.83 ± 0.60	60.15 ± 1.75^a3b3	17.67 ± 0.71^a3b3
400	13.67 ± 0.71	63.29 ± 0.71^a3b3	19.50 ± 0.71^a3b3
EAF (mg/kg) 100	16.33 ± 0.71	55.27 ± 2.13^a3b3	15.67 ± 0.67^a2b3
200	16.00 ± 0.37	55.27 ± 2.13^a3b3	16.83 ± 0.60^a3b3
400	12.67 ± 0.61	65.20 ± 2.20^a3b2	20.17 ± 0.70^a3b3
DW (10 ml/kg)	37.33 ± 1.12	0.00 ± 0.00	9.17 ± 0.40
CQ (25 mg/kg)	5.50 ± 0.56	85.34 ± 1.28^a3	28.33 ± 0.49^a3
AF (mg/kg) 100	24.33 ± 0.88	33.14 ± 3.54^a3b3	11.67 ± 1.20^b3
200	21.67 ± 0.49	40.53 ± 2.65^a3b3	13.83 ± 0.48^b3
400	15.67 ± 0.88	57.13 ± 2.48^a3b3	16.00 ± 1.06^a3b3

Data are expressed as mean ± SEM.
CF Chloroform fraction, EAF Ethyl acetate fraction, DW Distilled water, AF Aqueous fraction, CQ Chloroquine.
¹p < 0.05
²p < 0.01, p < 0.001
^acompared to negative controls
^bcompared to chloroquine

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