Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice

Table 5 The effects of E. globulus leaf solvent fractions against P. berghei infected mice in Rane’s test

Treatments	% parasitemia (D7)	%parasitemia suppression	Mean survival time (day)
2%tween80 (10 ml/kg)	36.00 ± 1.29	–	8.17 ± 0.70
CQ (25 mg/kg)	0.00 ± 0.00	100.00 ± 0.00^a3	30.00 ± 0.48^a3
CF (mg/kg) 100	17.50 ± 0.96	51.17 ± 2.82^a3b3	15.17 ± 0.65^a3b3
200	13.17 ± 0.60	63.46 ± 0.78^a3b3	16.67 ± 0.88^a3b3
400	11.67 ± 0.71	67.60 ± 1.63^a3b3	20.83 ± 0.54^a3b3
EAF (mg/kg) 100	16.33 ± 0.61	54.58 ± 1.07^a3b3	15.33 ± 0.42^a3b3
200	14.83 ± 0.60	58.53 ± 2.38^a3b3	16.83 ± 0.48^a3b3
400	10.33 ± 0.67	71.11 ± 2.13^a3b3	22.33 ± 0.71^a3b3
DW (10 ml/kg)	37.83 ± 1.40	–	7.83 ± 0.48
CQ (25 mg/kg)	0.00 ± 0.00	100.00 ± 0.00^a3	30.00 ± 0.48^a3
AF (mg/kg) 100	24.17 ± 0.87	32.15 ± 4.46^a3b3	11.67 ± 0.71^a3b3
200	21.33 ± 0.76	40.38 ± 2.80^a3b3	12.67 ± 0.56^a3b3
400	15.50 ± 0.43	56.66 ± 1.99^a3b3	16.67 ± 0.67^a3b3

Data are expressed as mean ± SEM.
CF Chloroform fraction, EAF Ethyl acetate fraction, DW Distilled water, AF Aqueous fraction, CQ Chloroquine
¹p < 0.05
²p < 0.01, p < 0.001
^acompared to negative controls
^bcompared to chloroquine

ISSN: 2662-7671