Table 4 EORTC QLQ-C30 and H&N35 scales over 3 months of follow-up

 Physical functioning

89.2 (14.1)

82.1 (14.7)

−7.1 (6.2)

83.6 (12.3)

80.7 (14.6)

−2.9 (1.8)

0.03

 Role functioning

87.9 (14.9)

85.6 (12.2)

−2.3 (2.5)

87.1 (19.1)

86.6 (19.4)

−0.5 (0.9)

> 0.05

 Emotional functioning

79.8 (16.0)

75.6 (10.8)

−4.2 (5.7)

75.6 (19.8)

78.8 (21.3)

−3.2 (3.9)

> 0.05

 Cognitive functioning

77.2 (22.7)

77.9 (16.6)

0.7 (0.9)

77.0 (20.1)

77.9 (21.7)

0.9 (1.1)

> 0.05

 Social functioning

73.0 (24.0)

76.9 (20.3)

3.9 (5.1)

76.7 (23.7)

78.4 (21.0)

1.7 (2.1)

> 0.05

 Fatigue

36.9 (16.8)

32.0 (21.1)

−4.9 (5.3)

32.9 (21.0)

31.9 (11.1)

−1 (1.2)

0.04

 Nausea/Vomiting

10.3 (19.2)

7.7 (13.6)

−2.6 (1.8)

10.3 (12.6)

9.2 (15.5)

−1.1 (1.3)

> 0.05

 Pain

21.8 (12.6)

16.4 (16.7)

−5.4 (6.7)

19.4 (15.2)

18.7 (17.7)

−0.7 (1.1)

0.02

 Dyspnea

16.2 (23.4)

12.1 (18.7)

−4.1 (6.1)

15.9 (18.8)

13.8 (15.8)

−2.1 (5.8)

> 0.05

 Insomnia

26.9 (27.5)

23.6 (22.1)

−3.3 (4.5)

26.7 (19.9)

25.4 (25.0)

−1.3 (2.1)

> 0.05

 Appetite loss

22.7 (26.7)

13.8 (20.9)

−8.9 (9.1)

20.9 (19.1)

16.4 (21.2)

−4.5 (7.2)

0.02

 Constipation

19.8 (15.2)

13.2 (12.5)

−6.6 (5.9)

17.1 (20.4)

18.2 (18.1)

1.1 (1.3)

0.01

 Diarrhea

14.8 (21.3)

12.4 (17.8)

−2.4 (2.9)

14.2 (17.6)

13.3 (17.6)

−0.9 (1.1)

> 0.05

 Financial problems

24.1 (20.1)

23.1 (14.1)

−1 (1.5)

24.6 (16.7)

23.9 (11.9)

−0.7 (1.2)

> 0.05

 Pain

21.8 (12.6)

16.4 (16.7)

−5.4 (6.7)

19.4 (15.2)

18.7 (17.7)

−0.7 (1.1)

0.02

 Swallowing

38.3 (26.6)

23.9 (21.5)

−14.4 (21.3)

35.0 (22.4)

30.9 (21.9)

−4.4 (7.9)

0.01

 Senses (taste/smell)

28.1 (19.0)

24.8 (28.1)

−3.3 (4.5)

30.6 (22.7)

27.7 (18.1)

−2.9 (3.9)

> 0.05

 Speech

29.4 (26.4)

21.5 (25.7)

−7.9 (8.9)

28.5 (24.0)

22.4 (24.7)

−6.1 (7.7)

> 0.05

 Social eating

32.0 (27.5)

28.5 (27.0)

−3.5 (4.2)

28.9 (25.3)

26.1 (18.9)

−2.8 (5.1)

> 0.05

 Social contact

23.0 (21.1)

22.7 (24.7)

−0.3 (0.9)

20.9 (20.1)

18.9 (20.3)

−2 (3.4)

> 0.05

 Sexuality

NA

NA

NA

NA

NA

NA

 Teeth

44.2 (30.6)

34.0 (29.1)

−10.2 (13.9)

40.9 (23.8)

31.2 (21.0)

−9.7 (14.9)

> 0.05

 Opening mouth

36.5 (31.9)

30.2 (20.4)

−6.3 (8.7)

34.9 (22.9)

27.4 (28.1)

−7.5 (9.1)

> 0.05

 Dry mouth

56.2 (18.6)

51.7 (19.9)

−4.5 (9.7)

50.1 (19.3)

49.8 (20.1)

−0.3 (1.2)

0.02

 Sticky saliva

45.8 (32.3)

36.8 (26.1)

−9 (12.9)

44.7 (23.9)

33.6 (22.9)

−11.1 (13.4)

> 0.05

 Coughing

31.0 (24.9)

24.5 (24.0)

−6.5 (8.7)

30.8 (21.9)

27.5 (21.7)

−3.3 (4.1)

> 0.05

 Feeling ill

32.3 (26.3)

30.3 (25.0)

−2 (4.7)

34.0 (23.2)

31.1 (23.4)

−2.9 (6.1)

> 0.05