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Table 6 Mean ± SD Zone of Inhibition of Symphonia globulifera and Allophylus abyssinicus Extracts and Combinations against Candida albicans

From: Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Extract

Mean ± SD Diametric Zone of Inhibition (mm) of Candida albicans

Fluconazole

1000

mg/ml

500

mg/ml

250

mg/ml

125

mg/ml

62.5

mg/ml

31.25

mg/ml

15.62

mg/ml

7.81 mg/ml

3.90

mg/ml

1.95

mg/ml

AALW

0

0

0

0

0

0

0

0

0

0

32.75 ± 0.96

AALM

11.25 ± 0.96ac

3.25 ± 0.96a

0

0

0

0

0

0

0

0

32.00 ± 0.00

AASW

5.75 ± 6.28e

4.00 ± 4.28a

0

0

0

0

0

0

0

0

33.00 ± 0.83

AASM

12.00 ± 0.82ab

2.75 ± 1.50a

0

0

0

0

0

0

0

0

33.50 ± 1.00

SGLW

0

0

0

0

0

0

0

0

0

0

35.00 ± 2.45

SGLM

7.25 ± 0.50de

0

0

0

0

0

0

0

0

0

45.00 ± 0

SGSW

0

0

0

0

0

0

0

0

0

0

37.75 ± 0.96

SGSM

13.00 ± 1.41a

0

0

0

0

0

0

0

0

0

43.25 ± 2.50

SGLW + AALW

0

0

0

0

0

0

0

0

0

0

33.25 ± 0.96

SGLW + SGLM

0

0

0

0

0

0

0

0

0

0

33.00 ± 0.82

AASW + AALW

0

0

0

0

0

0

0

0

0

0

33.25 ± 0.96

SGLM + AASW

0

0

0

0

0

0

0

0

0

0

33.25 ± 1.26

SGLW + AASW

9.00 ± 0.82bcd

5.25 ± 0.96a

0

0

0

0

0

0

0

0

33.50 ± 0.58

AALW + SGLM

9.00 ± 0.82bcd

5.25 ± 096a

0

0

0

0

0

0

0

0

34.00 ± 0.00

  1. a−j In columns mean values sharing a superscript letter are not significantly different (p > 0.05) as based on the LSD multiple Comparison test
  2. AALW Allophylus abyssinicus leaf water extract, AALM Allophylus abyssinicus leaf methanol extract, AASW Allophylus abyssinicus stem bark water extract, AASM Allophylus abyssinicus stem bark methanol extract, SGLW Symphonia globulifera leaf water extract, SGLM Symphonia globulifera leaf methanol extract, SGSW Symphonia globulifera stem bark water extract, SGSM Symphonia globulifera stem bark methanol extract