Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Lukubye, Ben; Ajayi, Clement Olusoji; Wangalwa, Rapheal; Kagoro-Rugunda, Grace

doi:10.1186/s12906-022-03692-0

BMC Complementary Medicine and Therapies

Table 4 Mean ± SD Zone of Inhibition of Symphonia globulifera and Allophylus abyssinicus extracts and combinations against Escherichia coli

From: Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Extract	Mean ± SD Zone of Inhibition (mm) of Escherichia coli
Extract	1000 mg/ml	500 mg/ml	250 mg/ml	125 mg/ml	62.5 mg/ml	31.25 mg/ml	15.62 mg/ml	7.81 mg/ml	3.90 mg/ml	1.95 mg/ml	Cipro floxacin
AALW	26.75 ± 0.96^a	22.00 ± 0^a	20.00 ± 0^a	15.25 ± 0.96^a	10.25 ± 0.50^b	8.00 ± 0.00^b	4.50 ± 0.58^a	1.00 ± 0.82^a	0	0	37.00 ± 0
AALM	20.25 ± 0.50^d	13.75 ± 0.96^e	12.00 ± 0^d	9.00 ± 0^f	8.50 ± 0.58^c	7.00 ± 0.82^b	4.00 ± 0^ab	1.25 ± 0.50^a	0	0	36.50 ± 1.00
AASW	22.00 ± 0^bc	17.00 ± 0^d	11.25 ± 0.96^de	6.75 ± 0.50^g	4.00 ± 0^f	1.75 ± 0.50	0	0	0	0	37.00 ± 0.00
AASM	13.00 ± 0.82^h	8.75 ± 0.96^h	6.75 ± 0.50^g	3.50 ± 0.58^h	2.25 ± 0.50^g	0	0	0	0	0	32.75 ± 0.96
SGLW	26.00 ± 0.82^a	20.25 ± 0.50^b	16.25 ± 0.50^b	14.75 ± 0.50^a	12.00 ± 0^a	9.25 ± 0.96^a	4.50 ± 0.58^a	0	0	0	34.00 ± 2.45
SGLM	22.75 ± 0.96^b	19.00 ± 0.82^c	8.00 ± 1.83^g	0	0	0	0	0	0	0	32.00 ± 0.82
SGSW	15.75 ± 0.96^ef	9.75 ± 0.96^g	4.50 ± 1.29ⁱ	2.25 ± 0.50ⁱ	0	0	0	0	0	0	32.50 ± 1.0
SGSM	13.25 ± 0.50^gh	6.75 ± 0.50ⁱ	4.25 ± 0.50ⁱ	0	0	0	0	0	0	0	32.75 ± 0.96
SGLW + AALW	16.25 ± 0.96^e	13.25 ± 0.50^e	12.00 ± 0^d	10.25 ± 0.50^cd	7.50 ± 1.00^d	4.25 ± 2.50^def	0	0	0	0	34.00 ± 2.45
SGLW + SGLM	20.75 ± 1.50^cd	16.75 ± 0.96^d	13.75 ± 1.26^c	9.25 ± 0.50^ef	5.75 ± 1.50^e	0	0	0	0	0	38.50 ± 2.38
AASW + AALW	14.50 ± 0.58^fg	12.25 ± 0.50^f	11.00 ± 0.82^df	10.00 ± 0.82^de	7.00 ± 0.82^d	5.00 ± 0.82^ce	4.00 ± 0^ab	1.25 ± 0.96^a	0	0	35.00 ± 2.45
SGLM + AASW	20.00 ± 0.82^d	18.50 ± 0.58^c	14.75 ± 0.96^c	11.25 ± 0.50^b	7.75 ± 0.50^cd	5.50 ± 0.58^c	3.50 ± 0.58^b	0	0	0	32.75 ± 0.96
SGLW + AASW	20.25 ± 1.26^d	18.25 ± 0.50^c	14.00 ± 0^c	11.00 ± 0.82^bc	8.50 ± 0.58^c	5.25 ± 0.96^cd	2.75 ± 1.26^c	0	0	0	36.00 ± 1.83
AALW + SGLM	16.50 ± 1.29^e	13.00 ± 0.82^ef	10.50 ± 1.00^ef	7.25 ± 0.50^g	5.25 ± 0.96^e	3.50 ± 0.58^f	1.75 ± 0.50	0	0	0	34.50 ± 3.00

^a⁻^j In columns mean values sharing a superscript letter are not significantly different (p > 0.05) as based on the LSD multiple Comparison test
AALW Allophylus abyssinicus leaf water extract, AALM Allophylus abyssinicus leaf methanol extract, AASW Allophylus abyssinicus stem bark water extract, AASM Allophylus abyssinicus stem bark methanol extract, SGLW Symphonia globulifera leaf water extract, SGLM Symphonia globulifera leaf methanol extract, SGSW Symphonia globulifera stem bark water extract, SGSM Symphonia globulifera stem bark methanol extract

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ISSN: 2662-7671

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