Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Lukubye, Ben; Ajayi, Clement Olusoji; Wangalwa, Rapheal; Kagoro-Rugunda, Grace

doi:10.1186/s12906-022-03692-0

BMC Complementary Medicine and Therapies

Table 3 Mean ± SD Zone of Inhibition of Symphonia globulifera and Allophylus abyssinicus extracts and combinations against Staphylococcus aureus

From: Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk

Extract	Mean ± SD Zone of Inhibition (mm) of Staphylococcus aureus
Extract	1000 mg/ml	500 mg/ml	250 mg/ml	125 mg/ml	62.5 mg/ml	31.25 mg/ml	15.62 mg/ml	7.81 mg/ml	3.90 mg/ml	1.95 mg/ml	Ciproflo xacin
AALW	31.25 ± 0.50^a	30.00 ± 0.00^a	27.25 ± 0.50^a	24.00 ± 1.15^a	19.00 ± 0^a	7.25 ± 0.50^cd	3.75 ± 0.50^cd	0	0	0	20.50 ± 3.10
AALM	19.00 ± 0.00^de	14.50 ± 1.00^ghi	12.25 ± 0.96^fg	11.00 ± 0^df	8.50 ± 0.56^e	7.00 ± 0.00^d	3.00 ± 0.82^de	0.75 ± 0.96^g	0	0	24.00 ± 0.81
AASW	26.75 ± 1.50^b	24.50 ± 0.58^b	21.75 ± 0.50^b	19.75 ± 1.70^b	15.00 ± 0.00^b	9.75 ± 0.50^a	7.00 ± 0.82^a	3.25 ± 0.96^ab	0	0	20.25 ± 0.50
AASM	17.75 ± 0.96^eg	15.00 ± 0.82^fh	12.00 ± 0^fg	10.75 ± 0.96^ef	8.75 ± 0.96^e	7.25 ± 0.50^cd	4.75 ± 0.96^b	1.00 ± 1.41^fg	0	0	27.00 ± 0.82
SGLW	22.75 ± 0.96^c	17.25 ± 0.50^c	14.75 ± 0.50^d	12.00 ± 0^d	10.50 ± 0.58^d	8.00 ± 0^bc	6.25 ± 0.96^a	2.75 ± 0.50^bd	0	0	32.50 ± 1.00
SGLM	20.25 ± 0.50^d	16.00 ± 0.00^def	12.00 ± 0^fg	10.00 ± 0.82^fg	5.00 ± 0.00^g	3.00 ± 0.82^g	0	0	0	0	27.00 ± 0.00
SGSW	18.25 ± 0.96^e	15.25 ± 0.96^fg	12.75 ± 0.96^ef	10.00 ± 1.41^fg	7.00 ± 0.00^f	5.25 ± 0.50^f	3.50 ± 0.58^ce	1.25 ± 1.26^fg	0	0	24.00 ± 0
SGSM	18.00 ± 0.82^ef	16.50 ± 0.58^ce	12.50 ± 0.58^eg	10.00 ± 0^fg	7.00 ± 0.82^f	3.75 ± 0.96^g	3.00 ± 0.82^de	0	0	0	24.75 ± 0.96
SGLW + AALW	15.00 ± 0.82ⁱ	12.25 ± 0.96^k	10.25 ± 0.96^h	6.75 ± 0.50	5.00 ± 0.00^g	3.00 ± 0.82^g	0	0	0	0	18.25 ± 0.96
SGLW + SGLM	18.25 ± 0.96^e	14.75 ± 0.96^gh	12.75 ± 0.50^ef	9.25 ± 0.50^gh	6.75 ± 0.50^f	6.00 ± 0^ef	4.25 ± 0.96^bc	1.75 ± 0.50^deg	0	0	22.25 ± 1.71
AASW + AALW	15.50 ± 1.29^hi	13.00 ± 0.82^k	12.00 ± 0.00^fg	11.25 ± 0.96^de	10.00 ± 8.62^d	8.75 ± 0.50^b	7.00 ± 0.00^a	4.25 ± 0.50^a	1.50 ± 0.57^ab	0	22.75 ± 0.97
SGLM + AASW	15.25 ± 1.50ⁱ	12.75 ± 0.96^jk	10.25 ± 0.50^h	8.25 ± 0.50^h	7.00 ± 0.00^f	5.75 ± 0.96^f	3.50 ± 0.58^ce	2.00 ± 0.82^cdef	0.75 ± 0.50^c	0	25.75 ± 1.26
SGLW + AASW	17.75 ± 0.96^eg	16.75 ± 0.50^cd	15.75 ± 0.50^c	14.00 ± 0^c	11.50 ± 1.29^c	7.25 ± 0.96^cd	4.25 ± 0.50^bc	2.50 ± 0.58^be	1.00 ± 0.82^bc	0	22.00 ± 0
AALW + SGLM	16.75 ± 0.50^fgh	13.50 ± 1.29^ij	13.00 ± 0^e	11.25 ± 0.96^de	9.75 ± 0.50^d	6.75 ± 0.50^de	5.00 ± 0.82^b	3.00 ± 0.82^bc	2.00 ± 0.82^a	0	23.50 ± 1.00

^a⁻^jIn columns mean values sharing a superscript letter are not significantly different (p > 0.05) as based on the LSD multiple Comparison test
AALW Allophylus abyssinicus leaf water extract, AALM Allophylus abyssinicus leaf methanol extract, AASW Allophylus abyssinicus stem bark water extract, AASM Allophylus abyssinicus stem bark methanol extract, SGLW Symphonia globulifera leaf water extract, SGLM Symphonia globulifera leaf methanol extract, SGSW Symphonia globulifera stem bark water extract, SGSM Symphonia globulifera stem bark methanol extract

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ISSN: 2662-7671

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