Table 1 The dosage of main components in TAZF administered by gavage in rats
From: Toxicity and toxicokinetics of the ethanol extract of Zuojin formula
Dose | TAZF (g/kg) | Berberine (mg/kg) | Epiberbrine (mg/kg) | Coptisine (mg/kg) | Palmatine (mg/kg) | Jatrorrhizine (mg/kg) | Columbamine (mg/kg) | Evodiamine (mg/kg) | Rutecarpine (mg/kg) |
|---|---|---|---|---|---|---|---|---|---|
High | 3.7 | 545.01 | 50.69 | 93.24 | 116.18 | 17.39 | 35.15 | 52.17 | 46.99 |
Medium | 1.2 | 176.76 | 16.44 | 30.24 | 37.68 | 5.64 | 11.40 | 16.92 | 15.24 |
Low | 0.4 | 58.92 | 5.48 | 10.08 | 12.56 | 1.88 | 3.80 | 5.64 | 5.08 |