Table 6 IC50 µg/mL ± SEM of cytotoxicity of PSD remedy and its ingredients against two types of cancer cell lines and one non-cancerous cell line using Sulforhodamine B (SRB) assay (n = 3)
Plant species | Code | %Yield (w/w) | IC50 µg/mL ± SEM and Selective index (SI) | ||
|---|---|---|---|---|---|
HepG2 | KKU-M156 | HaCaT | |||
Bouea macrophylla Griff | BM95 | 3.52 | 36.15 ± 0.54**** (SI = ND) | 60.53 ± 1.08**** (SI = ND) | > 100**** |
Caesalpinia sappan L | CS95 | 8.17 | 6.44 ± 0.54**** (SI = 6.7) | 4.77 ± 0.57**** (SI = 9.0) | 43.14 ± 1.46**** |
Citrus aurantiifolia (Christm.) | CA95 | 2.63 | 92.96 ± 2.22**** (SI = ND) | > 100**** (SI = ND) | > 100**** |
Dracaena cochinchinensis (Lour.) S.C. Chen | DC95 | 10.45 | 7.72 ± 1.87**** (SI = 5.2) | 5.27 ± 5.01**** (SI = 7.7) | 40.47 ± 0.39**** |
Heliciopsis terminalis (Kurz) | HT95 | 1.99 | 44.50 ± 1.01**** (SI = ND) | 43.42 ± 0.29**** (SI = ND) | > 100**** |
Jasminum sambac (L.) Aiton | JS95 | 8.59 | 95.01 ± 0.41**** (SI = ND) | 85.77 ± 2.25**** (SI = ND) | > 100**** |
Kaempferia galanga L | KG95 | 3.49 | 7.81 ± 2.39**** (SI = ND) | 32.95 ± 3.75**** (SI = ND) | > 100**** |
Ligusticum chuanxiong Hort | LC95 | 8.50 | 11.87 ± 4.43**** (SI = ND) | 43.55 ± 4.02**** (SI = ND) | > 100**** |
Mammea siamensis T. Anderson | MS95 | 19.41 | 5.67 ± 0.32**** (SI = 9.0) | 7.52 ± 1.05**** (SI = 6.8) | 51.20 ± 0.68**** |
Mesua ferrea L | MF95 | 11.57 | 7.10 ± 0.16**** (SI = 7.3) | 27.17 ± 2.86**** (SI = 1.9) | 51.99 ± 0.37**** |
Myristica fragrans Houtt | MYF95 | 2.88 | 5.67 ± 0.32**** (SI = 4.6) | 5.02 ± 3.14**** (SI = 5.2) | 26.32 ± 2.67**** |
Nelumbo nucifera Gaertn | NN95 | 8.08 | > 100**** (SI = ND) | > 100**** (SI = ND) | > 100**** |
Prasachandaeng remedy | PSD95 | 13.62 | 10.45 ± 1.98**** (SI = 5.3) | 4.53 ± 0.74**** (SI = 12.2) | 55.45 ± 1.73**** |
Vincristine sulfate | - | - | 0.012 ± 0.0005 (SI = 0.00058) | 0.0026 ± 0.001 (SI = 0.0026) | 0.000007 ± 0.00 |