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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Metformin and Gegen Qinlian Decoction boost islet α-cell proliferation of the STZ induced diabetic rats

Fig. 3

GQD and metformin improved the morphology of diabetic islet by increasing the total islet cell number. A, HE staining of the pancreas; B, Immunohistochemical staining of insulin in the pancreas; C, Insulin positive cell number of islets. Diabetes significantly decreased β-cell number compared to the control (p < 0.001); D, Total cell number of islets. Diabetes significantly decreased total islet cell number compared to the control (p < 0.01) and the total islet cell number in the GQD or metformin group was increased compared to the diabetes group (p < 0.05); E, Insulin positive cell ratio of islets; F, Average islet area of different groups. Diabetes decreased islet area compared to the control group (p < 0.01). (* p < 0.05, ** p < 0.01, *** p < 0.001; Scale bar: 50 μm; magnification: 400×; n = 17–26)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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