Fig. 4From: Human liver microsomes study on the inhibitory effect of plantainoside D on the activity of cytochrome P450 activityTime-dependent evaluation. A The inhibition of CYP3A was found to be time-dependent, whereas CYP1A2 and CYP2D6 was not affected by incubation time. B-C Time-dependet inhibition of CYP3A in the presence of 0, 2, 5, 10, 20, and 50 μM plantainoside D (B). The values of KI and Kinact were calculated as 1.28 and 0.039 (C)Back to article page