Fig. 2

Predicted mechanisms of QHF in treating B cell lymphoma. A. The dot plot of GO functional enrichment of QHF. B. The dot plot of KEGG pathway enrichment analysis of QHF. C. The KEGG pathway diagram of Toll-like receptor signaling pathway [49,50,51]. It shows that QHF could target AKT, NF-κB, p38, ERK, and JNK to activate PI3K/Akt signaling pathway, MAPK, and NF-κB signaling pathways. D. Representative images of molecular docking show that the active components of QHF bind to TLR2, ERK, JNK, and AKT primarily with hydrogen bonds