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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

Fig. 5

Oridonin improves LSS induced EC dysfunction and oxidative stress by activating NRF2. A-C Results of the western blot revealed that oridonin treatment counteracted the LSS-induced downregulation of eNOS and SOD by activating NRF2. ##P < 0.01 vs. LSS (−) + oridonin (−) + NRF2 siRNA (−); **P < 0.01 vs. LSS (+) + oridonin (−) + NRF2 siRNA (−); $$P < 0.01 vs. LSS (+) + oridonin (+) + NRF2 siRNA (−). LSS, low shear stress; eNOS, endothelial nitric oxide synthase; SOD, superoxide dismutase; siRNA, small interfering RNA

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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