Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model

Table 1 Effect of Cisplatin (CisPT) and AHE treatment on body weight of rats

Data expressed as mean ± SEM (n = 8). Asterisks ^*, ^** indicated a significant difference in the final body weight of the group Vs. Control group at p < 0.05 and p < 0.001 respectively, ⁺⁺ indicated significant difference of final body weight of group Vs. CisPT-treated group at p < 0.001, ^## indicated significant difference of final body weight of AHE (200 mg/kg) + CisPT treated group Vs. AHE (400 mg/kg) + CisPT treated group at p < 0.001. Non-significant difference (p > 0.05) was recorded between the control and AHE alone treated group in all parameters. (One-way ANOVA followed by Tukey’s multiple comparison tests). Sily-Silymarin

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