Fig. 4
Cerebral cortex sections from the untreated group showing normal histological features of brain morphology with well-shaped neurons. Cisplatin (CisPT, 12Â mg/kg) shot induces severe damage in cerebral cortex regions. Sections of Acacia hydaspica ethyl acetate extract (AHE) pretreated group at 200Â mg/kg for 16Â days showed significant protection and rescue of neuron damages with slight signs of the CisPT damage tissues. Sections of AHE (400Â mg/kg) pretreated for 16Â days showed brain regions with fewer damaged tissues than CisPT group and showed near-to normal brain morphology with well-organized nuclei devoid of vacuolation and irregular features