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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway

Fig. 3

Effects of FMA on Iba-1 + microglia and GFAP + astrocytes in the CA1 area. Iba-1 + microglia in (A) sham group 10x (a) 200x, (B) TI-induced group 10x, (b) 200x, (C) TI-induced + FMA (400 mg/kg) group 10x (c) 200 × and GFAP + astrocyte in the CA1 area in (D) sham group 10x (d) 200x, (E) TI-induced group 10x, (e) 200x, (F) TI-induced + FMA (400 mg/kg) group 10x (f) 200x. In the TI-induced group, Iba-1 + were significantly increased and GFAP + cells showed larger and thicker processes in the CA1 region of the hippocampus compared with sham and FMA-pretreated groups. (G) Graph represent the immunoreactive Iba1 + and (H) GFAP + cells number (% of sham). Data are presented as mean ± SEM, n = 3/group, one-way ANOVA with a Tukey post-hoc tests; (#p < .05) compared with sham and (*p < .05) compared with Stroke

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