Fig. 6From: Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse modelWenyang Huazhuo Tongluo Formula and KC7F2 can significantly inhibit the expression of HIF-1α in bleomycin-induced SSc mouse model. The effect of Wenyang Huazhuo Tongluo Formula and KC7F2 on the expression of HIF-1α was observed by immunofluorescence staining, in which HIF-1α were labeled with green fluorescence, while the nuclear was stained by DAPI with blue fluorescence. The mean values ± SD was shown for each bar. * (P < 0.05) or ** (P < 0.01) or *** (P < 0.001) represents significance, ns represents no significance. Original magnification: × 20. BLM: Bleomycin, WYHZTL: Wenyang Huazhuo Tongluo formulaBack to article page