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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model

Fig. 3

Wenyang Huazhuo Tongluo Formula can alleviate the pulmonary vascular leakage in bleomycin-induced SSc mouse model. A The concentration of albumin in BALF of different group mice was detected by ELISA assay. Then, the expression of VE-cadherin (B) and claudin-5 (C) were detected by immunofluorescence staining, in which VE-cadherin and claudin-5 were labeled with green fluorescence, while the nuclear was stained by DAPI with blue fluorescence. The mean values ± SD was shown for each bar. * (P < 0.05) or ** (P < 0.01) or *** (P < 0.001) represents significance, ns represents no significance. Original magnification: × 20. BLM: Bleomycin, WYHZTL: Wenyang Huazhuo Tongluo formula

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