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Table 1 Inhibition models and related parameters of selected glucosidase inhibitors from D. angustifolia Roxb

From: Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study

Compound

Mode of inhibition

Ki (μM)

Km (μM)

18

Uncompetitive

21.08 ± 12.25

0.12 ± 0.03

5

Noncompetitive

39.88 ± 8.47

0.14 ± 0.01

8

Competitive

11.16 ± 0.99

0.18 ± 0.01

6

Mixed

57.76 ± 1.67

0.17 ± 0.01

9

Mixed

54.42 ± 15.76

0.17 ± 0.01

22

Mixed

7.00 ± 1.97

0.04 ± 0.01

24

Mixed

43.96 ± 0.88

0.08 ± 0.01