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Table 9 In-vivo results of synthesized compounds against the standard drug

From: Phytochemistry, anti-diabetic and antioxidant potentials of Allium consanguineum Kunth

Groups

Dose μg/kg

Blood Glucose Level(mg/dl)

Decrease in Blood Glucose (mg/dl)

Change in body weight (gm)

0 day

4th day

7th day

10th day

15th day

Diabetic control

0.35 ml

477

482

502

513

525

-48

−13.6

Normal control saline

0.35

124

110

102

95

91

33

–

Glibenclamide

0.5

472

302

256

211

198

274

+ 10.1

Comp 1

1

500

411

387

371

311

292

119

+ 7.2

2

250

420

394

345

217

215

205

+ 5.6

3

125

441

433

414

402

394

47

+ 4.3

4

62.5

381

372

364

352

344

37

+ 4.1

5

31.25

415

407

398

381

379

36

+ 2.1

Comp 2

1

500

457

403

362

304

256

201

+ 7.3

2

250

467

462

444

408

355

112

+ 3.3

3

125

436

430

421

393

368

68

−3.5

4

62.5

385

358

348

335

326

59

−4.4

5

31.25

451

447

430

424

418

33

−6.6