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Table 7 Alpha glucosidase, alpha amylase and DPPH inhibitory potentials of isolated compounds 1 and 2

From: Phytochemistry, anti-diabetic and antioxidant potentials of Allium consanguineum Kunth

Samples

Conc (μg/ml)

Alpha glucosidase

Alpha amylase

DPPH

Percent Inhibition (mean ± SEM)

IC50 (μg/ml)

Percent Inhibition (mean ± SEM)

IC50 (μg/ml)

Percent Inhibition (mean ± SEM)

IC50 (μg/ml)

Comp 1

1000

85.37 ± 0.08ns

7.93

85.23 ± 0.22ns

28.01

89.24 ± 0.79**

6.19

500

81.65 ± 0.44ns

79.45 ± 0.90ns

85.43 ± 1.39*

250

76.35 ± 1.42ns

74.90 ± 0.60ns

80.48 ± 0.25**

125

72.21 ± 0.39ns

67.00 ± 0.30*

76.47 ± 0.04***

62.5

67.66 ± 0.78ns

58.90 ± 0.45**

71.47 ± 0.44***

Comp 2

1000

77.82 ± 0.86***

14.63

81.61 ± 1.70**

24.82

87.62 ± 0.58***

7.64

500

72.67 ± 0.67***

74.33 ± 1.20***

82.35 ± 0.23***

250

67.46 ± 1.67***

68.33 ± 0.49***

78.36 ± 0.84***

125

63.58 ± 0.92***

64.70 ± 1.60**

73.62 ± 0.25***

62.5

61.36 ± 1.15**

59.33 ± 0.67**

69.16 ± 0.16***

Acarbose

1000

89.50 ± 1.00

12.57

87.49 ± 0.60

13.13

  

500

83.00 ± 0.00

82.28 ± 1.94

  

250

77.50 ± 0.57

77.08 ± 1.04

–

–

125

73.53 ± 0.55

72.37 ± 0.56

  

62.5

67.63 ± 0.33

65.93 ± 1.73

  

Ascorbic acid

     

92.55 ± 0.35

4.32

     

87.84 ± 0.26

–

–

–

–

–

83.33 ± 0.88

     

80.54 ± 0.54

     

75.67 ± 0.19

  1. All values are taken as Mean ± SEM (n = 3). The P values less than 0.05 were considered as statistically significant. Values significantly different in comparison to standard drug i.e.** = P < 0.01 and *** = P < 0.001