Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology

Table 3 Top 15 potential targets in the 56 potential targets PPI network

Protein Name	Degree	Betweenness Centrality	Protein Name	Degree	Betweenness Centrality
IL6	51	0.059767121	IL6	51	0.059767121
IL1B	46	0.034930701	EGFR	43	0.041706178
TNF	46	0.030700549	VEGFA	46	0.038701872
VEGFA	46	0.038701872	IL1B	46	0.034930701
AKT1	45	0.034171523	AKT1	45	0.034171523
PTGS2	44	0.027625229	TNF	46	0.030700549
EGFR	43	0.041706178	ESR1	33	0.030204633
EGF	42	0.022481519	PTGS2	44	0.027625229
JUN	40	0.025683985	JUN	40	0.025683985
CCL2	39	0.015488887	EGF	42	0.022481519
MMP2	37	0.009780132	MAPK14	34	0.021812819
IL4	36	0.013415867	CCL2	39	0.015488887
TGFB1	35	0.009526729	IL4	36	0.013415867
MAPK14	34	0.021812819	CEBPB	20	0.011576047
ICAM1	33	0.005648341	CXCL10	27	0.011252843

ISSN: 2662-7671