Table 2 Top 15 potential targets in the PC-PT network according to degree and betweenness centrality
Protein Name | Degree | Betweenness Centrality | Protein Name | Degree | Betweenness Centrality |
|---|---|---|---|---|---|
PTGS2 | 54 | 0.277312173 | PTGS2 | 54 | 0.277312173 |
ESR1 | 46 | 0.153120648 | PTGS1 | 42 | 0.204507204 |
PTGS1 | 42 | 0.204507204 | ESR1 | 46 | 0.153120648 |
NOS2 | 19 | 0.032615148 | CXCR4 | 8 | 0.086469588 |
AKT1 | 15 | 0.01512124 | TNF | 12 | 0.060803175 |
GSK3B | 13 | 0.009859331 | CYP3A4 | 12 | 0.058290209 |
CYP3A4 | 12 | 0.058290209 | HMOX1 | 6 | 0.035902065 |
TNF | 12 | 0.060803175 | HIF1A | 4 | 0.035245261 |
ACTB | 10 | 0.013813159 | ICAM1 | 5 | 0.034843635 |
MAPK14 | 10 | 0.001209612 | NOS2 | 19 | 0.032615148 |
CEBPB | 9 | 0.007230542 | IL1B | 8 | 0.031406599 |
ANXA1 | 8 | 0.014493758 | TGFBR2 | 4 | 0.029023858 |
CXCR4 | 8 | 0.086469588 | IFNG | 4 | 0.016903104 |
IL1B | 8 | 0.031406599 | AKT1 | 15 | 0.01512124 |
IL6 | 6 | 0.009704189 | SERPINE1 | 5 | 0.014896122 |