Fig. 6

Predicted binding mode within the active site of the drug-target complexes obtained from Autodock vina. A kaempferol-AKT1; B luteolin-AKT1; C quercetin-AKT1; D kaempferol-IL6; E luteolin-IL6; F quercetin-IL6; G kaempferol-PTGS2; H luteolin-PTGS2; I quercetin-PTGS2; J kaempferol-TNF; K luteolin-TNF; L-quercetin-TNF). The proteins were presented as cartoon modes, and molecules were presented as ball and stick models. Active site amino acid residues are represented as lines. Dotted blue lines in these pictures represent hydrogen bonds with distance units of ˚ A, dotted khaki lines represent π-Cation interactions, dotted red lines represent π-Stacking (parallel) interactions and dotted grey lines represent hydrophobic interaction. Other O and N atoms are colored red and blue, respectively