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Table 6 Effect of the extract on the hepatic function

From: Lipotropic activities of aqueous extract of Vernonia guineensis Benth. in Wistar rats fed high fat diet

Groups

RW

Liver

RW

Kidneys

AST

(U/L)

ALT

(U/L)

γ-GT

(U/L)

ND + distilled water (Normal Control)

0.0270 ± 0.005b

0.0072 ± 0.00006

69.97 ± 13.36a

80.22 ± 12.71a

0.98 ± 0.23a

HFD + distilled water ( Negative Control)

0.035 ± 0.0057b

0.0081 ± 0.00025

87.64 ± 15.17

98.78 ± 10.26

2.65 ± 1.70

HFD + AEVG

(400 mg/kgBW)

0.024 ± 0.0023a,b

0.0074 ± 0.00082

62.96 ± 33.45

110.34 ± 19.56

1.64 ± 1.14

HFD + Fenofibrate (100 mg/kgBW)

(Positive Control)

0.018 ± 0.002 a

0.0062 ± 0.00065a

76.12 ± 18.05

125.13 ± 13.80

1.84 ± 0.75

  1. ND Normal diet, HFD high fat diet, AEVG aqueous extract of Vernonia guineensis, RW relative weight, AST aspartate aminotransferase, ALT alanine aminotransferase, γ-GT gammaglutamyl transferase
  2. Values were expressed as mean ± standard deviation
  3. an = 5 and bp < 0.05; significantly different compared to the negative control and the positive control respectively