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Table 5 Effect of AEVG on hepatic accumulation and faecal excretion of triglycerides and cholesterol

From: Lipotropic activities of aqueous extract of Vernonia guineensis Benth. in Wistar rats fed high fat diet

Groups

Liver

Faeces

TG

(mg/g of liver)

TC

( mg/g of liver)

TG

( mg/g of faeces)

TC

( mg/g of faeces)

ND + distilled water (Normal Control)

9.73 ± 1.77ab

20.06 ± 1.68b

110.46 ± 12.08ab

57.13 ± 15.78b

HFD + distilled water ( Negative Control)

48.65 ± 8.81b

27.31 ± 9.94b

191.64 ± 6.77b

46.41 ± 6.25b

HFD + AEVG

(400 mg/kgBW)

32.48 ± 9.98a,b

11.99 ± 2.03a

198.43 ± 5.82b

72.79 ± 7.41a

HFD + Fenofibrate

(100 mg/kgBW)

(Positive Control)

16.10 ± 13.83a

4.97 ± 2.19a

257.90 ± 20.07a

63.34 ± 2.23a

  1. ND Normal diet, HFD high fat diet, AEVG aqueous extract of Vernonia guineensis, TG triglycerides, TC total cholesterol
  2. Values were expressed as mean ± standard deviation
  3. an = 5 and bp < 0.05; significantly different compared to the negative control and the positive control respectively